May 9, 2025

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Better health begins with ideas

 

Editors’ Note

On Monday, President Donald Trump issued a new executive order that restricts funding for gain-of-function research in the United States and other countries, including China. Gain-of-function research, where scientists adapt and enhance pathogens such as viruses or bacteria to learn how those agents threaten health, has been the subject of controversy for years and is accused of being the origin of COVID-19.  

 

However, a broad or poorly defined ban on gain-of-function research could impede studies into disease prevention, antibiotic resistance, immunology, and vaccines. To help the political and scientific community move beyond an impasse, Texas A&M University’s Ben C. Snyder proposes creating an independent government authority for bio-responsibility. Snyder argues that the body should create a risk-based regulatory framework and consolidate oversight functions to foster public trust and reduce the risks associated with gain-of-function research.  

 

The edition then returns to the conversation around the global health landscape sans U.S. federal funding. Ipas CEO Anu Kumar and Development Director Pansi Katenga describe how the dismantling the U.S. Agency for International Development (USAID) presents an opportunity to reimagine support for sexual and reproductive health and rights. The authors note that the Helms Amendment and the Mexico City Policy are obsolete without U.S. aid funding, creating a chance for health systems and organizations worldwide to deliver abortion care.  

 

Next, Binaytara Foundation President and Cofounder Binay Shah outlines how USAID cuts will disrupt funding for programs providing human papillomavirus (HPV) vaccines to millions annually. Without access to the HPV vaccine that prevents cancers caused by the virus, women and girls in low- or middle- income countries, where more than 84% of cervical cancer deaths occur, will continue to suffer from the preventable illness.  

 

To wrap up the edition, nonprofit communications leader Emile Dawisha spotlights how Uganda is maximizing its public-private partnerships to sustain its progressive refugee policies and tackle disease threats amid the loss of U.S. foreign aid.    

 

Until next week!—Nsikan Akpan, Managing Editor, and Caroline Kantis, Associate Editor 

 

This Week’s Highlights

 

GOVERNANCE

U.S. President Donald Trump shows a signed document as he signs executive orders and proclamations in the Oval Office at the White House, in Washington, D.C., U.S., May 5, 2025.

A Bio-Responsibility Strategy for Gain-of-Function Research Oversight

by Ben C. Snyder

Controversy about research on dangerous pathogens requires the U.S. government to adopt a new governance approach

      

Read this story

GENDER

A cervical cancer patient lays on a bed in the female ward of a cancer institute, in Dar es Salaam, Tanzania, on November 11, 2009.

USAID Cuts Could Sever HPV Prevention 

by Binay Shah 

Slashing global aid will limit access to the HPV vaccine and widen disparities in cervical cancer 

 

Read this story

GENDER

Women attend a talk on sexual health and HIV prevention organized by the Jesuit-founded Association Solidarite Vie e Santa (Association of Solidarity, Life and Health), in Ouagadougou, Burkina Faso.

Reimagining Sexual and Reproductive Health Without U.S. Involvement  

by Anu Kumar and Pansi Katenga

The Helms Amendment and the Mexico City Policy, also known as the Global Gag Rule, are moot without U.S. aid funding 

      

Read this story

 

Figure of the Week

 

Though H5N1 case detections have dropped from their peak in the fall and winter of 2024, U.S. Centers for Disease Control and Prevention officials urged continued surveillance as cases could resurge if new flu subtypes appear. Researchers indicate that though cow-to-cow transmission is responsible for much of the spread, any seasonality in H5N1 could correspond to migratory bird patterns when poultry flocks and dairy cattle are at higher risk for fresh introductions.

Three line charts showing weekly H5N1 detections from January 2024 to April 2025. Limited surveillance may lead to underreporting. Annotation: H5N1 was detected in 125 dairy herds in December 2024
 

Recommended Feature

 

POVERTY

In Uganda’s Bidibidi refugee settlement, a Village Health Team member conducts an in-home health visit to a refugee mother and child.

Preserving Refugee Health in Uganda  

by Emile Dawisha

Amid U.S. funding cuts, Uganda works to protect its rapidly growing refugee population from deadly diseases 

 

Read this story

 

What We’re Reading

How to Fill the America-Shaped Hole in Global Health (New York Times)

 

Teens With Anxiety and Depression Spend More Time on Social Media (Nature)

 

Europe Unveils $565 Million Package to Retain Scientists, and Attract New Ones (STAT)

 

Zero-Alcohol Drinks Make Teens Think of Alcohol—So Why Are We Treating Them Like Soft Drinks? (Institute for Alcohol Studies)

 

Peru’s Illegal Mining Surges . . . and Destroys (Global Health Now)

 

UNAIDS to Slash Workforce by More Than Half as Funding by the United States and Other Big Donors Disappears (Washington Post)

 

Bill Gates Pledges His Remaining Fortune to the Gates Foundation, Which Will Close in 20 Years (Associated Press)

 

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